BLOOD SUGAR DYSREGULATION (DIABETES / PRE-DIABETES) AND IT'S EFFECT ON CONNECTIVE TISSUES (LIGAMENTS, TENDONS, & FASCIARead Now
DIABETES EFFECT ON CONNECTIVE TISSUES
"The correct establishment and maintenance of cell polarity are crucial for normal cell physiology and tissue homeostasis. Conversely, loss of cell polarity, tissue disorganization and excessive cell growth are hallmarks of cancer." From a 2011 issue of Cell Death & Differentiation (Epithelial Cell Polarity: A Major Gatekeeper Against Cancer?)
"Whereas the importance of cell proliferation in cancer is well recognized, the role cell polarity plays is only beginning to be appreciated. If cell proliferation and death are analogous to acceleration and brakes in a car, and metabolism is analogous to fuel, cell polarity can be compared with the steering wheel, which controls direction and maintains spatial relationships in traffic. Improper steering can result in significant damage even to a non-speeding car, and conversely, proper steering can prevent damage to a speeding car. similarly, we posit that loss of control over cell polarity can disrupt normal cell behavior and lead to initiation and progression of cancer." From a 2012 issue of the Annual Review of Cell and Developmental Biology (Cell Polarity As A Regulator of Cancer Cell Behavior Plasticity)
"Epithelial cells possess a distinctive apical–basal polarity and loss of polarity is frequently assumed to be a common feature of cancer progression. A widely accepted paradigm for cancer progression is that epithelial cells undergo a transition, during which they lose apical / basal polarity and become highly migratory. [These cells] penetrate the basement membrane, cross the endothelium and enter the lymphatic system or bloodstream through which they are rapidly disseminated. At ectopic sites in the body, the cells colonize surrounding tissue to form metastases." From a 2013 issue of Philosophical Transactions of the Royal Society B: Biological Sciences (Cell Polarity in Morphogenesis and Metastasis)
"Breast cancer is one of the leading causes of cancer related death in women worldwide. The developing mammary gland is a highly proliferative and invasive tissue, and some of the developmental programs may be aberrantly activated to promote breast cancer progression. In the breast, luminal epithelial cells exhibit apical–basal polarity, and the failure to maintain this organizational structure, due to disruption of polarity complexes, is implicated in promoting hyperplasia and tumors." From the June 2016 edition of the Journal of Cellular Biochemistry (Cell Polarity Proteins in Breast Cancer Progression)
This helps explain why we should have a slightly negative overall polarity. If you really want to understand this whole relationship better, read Dr. Sircus' cool article from last December, ELECTROMAGNETIC PROPERTIES OF CANCER. Just remember that none of what you are reading today is 'way out there' or confined to alternative medicine. It's mainstream. In fact, DR. OTTO WARBURG won the Nobel Prize for Medicine back in 1931 for his pioneering work on this topic --- a topic that's getting increasingly wider play with every passing day (HERE). Now lets move on to the relationship of the fascia system to the lymphatic system.
FASCIA, CANCER, AND YOUR LYMPHATICS
Our body is under a constant invasion from every sort of microbe you can imagine. A failure to properly deal with these invaders by our immune system (80% OF WHICH LIVES IN THE GUT) would mean a quick death. The lymph system carries germs or other things that should not be there to the lymph nodes (larger nodules of lymphatic tissue), where they are filtered out. Because B-Cells (white blood cells that make antibodies) and T-CELLS (white blood cells that either eat the bad guys or throttle back on immune response to lessen one's chances of developing AUTOIMMUNITY) live in these nodes, said invaders are recognized, marked for destruction, and wiped out.
For reasons that are not totally clear, once cancer makes it as far as the lymph nodes, it actually has a better chance of survival, which is why finding cancer in lymph nodes is not a good thing. Instead of activating the immune system against cancer like would happen in the presence of germs, cancer in the lymphatics suppresses the immune system. Listen to the first two sentences of Lymphatic Vessels in Cancer Metastasis: Bridging the Gaps, from a 2006 issue of Oxford Academic's Carcinogenesis.
"Distant organ metastasis is the most important factor in determining patient survival in cancer. This is thought to occur via the body's own systems for transporting fluid and cells, the blood vascular and lymphatic systems. Cancer cells may exploit these vascular systems by expressing growth factors, which alter the normal pattern of angiogenesis and lymphatic vessel growth (lymphangiogenesis), thus creating conduits for tumour metastasis."
In a paper presented to 7th Interdisciplinary World Congress on Low Back a Pelvic Pain, Australian massage therapist Peter Lelean (Migratory Fascia - A Role In Ductal Carcinoma In Situ?) wrote, "Treatment of shoulder pain in women revealed common pelvic misalignments and anomalies in upper thoracic myofascia, where distorted strain patterns may inhibit lymphatic function, therefore becoming a risk factor in Ductal Carcinoma In Situ." After talking about the part of the latisimus dorsi not associated with the THORACOLUMBAR FASCIA, he invoked TRAVELL & SIMMONS, quoting them as saying clear back in 1983, "Entrapment of this lymph duct by passage between tense fibers of an involved pectoralis major muscle, may cause edema of the breast. This seems to coincide with the reportedly higher proliferation of ductal accretions in the upper outer quadrant."
Osteopath Steve Matta expounded on this when he said in last year's Lymphatics, "The lymphatic channels course through fascia. Fascia can sometimes be nice and loose or it can be super tight. If all goes well, the lymph is able to move through lymphatic channels without any problems and we can properly fight infections. Let’s think about this for a second…if the lymphatic channels are located in the fascia and the fascia can tighten up, what do you think happens to the flow of lymph when the fascia is tight? That’s right, it slows down." So, beyond things like lymphedema, other problems can occur. Sometimes bad problems.
Something like seven and a half gallons of lymph (interstitial fluid) courses through the lymphatic system each day. A failure to move this fluid means you increase the amount of cellular waste in the body, which causes inflammation, which then EPIGENETICALLY turns on the genes said to cause cancer. In an article called Fascia, Muscles, and the Lymph System, renowned fascia therapist Victoria L. Magown wrote, "Fascia plays an important role with our Lymph System. The majority of our Lymph System lives in the Superficial Fascia right under the skin. The Fascia and Muscles need to be flexible, supple and strong to move the lymph through the lymphatic vessels. This is done by the Fascia and Muscles contracting which constricts the lymphatic vessels and pushes the lymph fluid forward. Check valves prevent the fluid from flowing backward. Since the lymphatic system does not have a heart to pump it, its upward movement depends on the motions of the Fascia, Muscles and pumping joints." The thing is folks, it's not like I haven't shown you all of this previously (SEE MY ARTICLE ON THE PRIMO-LYMPHATIC SYSTEM).
MORE ON THE RELATIONSHIP BETWEEN FASCIA & CANCER
COULD FIXING YOUR FASCIA HELP WITH CANCER?
"Adipocytes might arise from vascular stromal cells. Here, we identified adipose precursor cells resident in fascia, an uninterrupted sheet of connective tissue that extends throughout the body. Our findings suggest a novel model for the origin of adipocytes from the fascia, which explains both neogenesis and expansion of adipose tissue. Fascial preadipocytes generate adipose cells to form primitive adipose lobules in superficial fascia, a subcutaneous nonadipose tissue. With continuous adipogenesis, these primitive adipose lobules newly formed in superficial fascia may be the rudiment of subcutaneous adipose tissue."
There are any number of studies linking this all together. Two years ago the journal Trends in Biotechnology (Biomechanical and Biochemical Remodeling of Stromal Extracellular Matrix in Cancer) concluded that, "During cancer progression, epithelial cells undergo genetic alterations which, together with stromal changes including ECM remodeling, disturb the homeostatic dynamics of the epithelium. A parallel organization of stromal ECM fibrils is associated with tumorigenic responses. In an emerging paradigm, continuous and progressive regulation via mechanical forces and aberrant signaling are believed to be responsible for tumor-associated ECM remodeling."
A year prior, Research Gate (Tumor Mechanics and Metabolic Dysfunction) said, "Desmosplasia is a characteristic of most solid tumors and leads to fibrosis through abnormal extracellular matrix (ECM) deposition and remodeling. The resulting stiff tumor stroma not only compromises vascular integrity to induce hypoxia, but also promotes aggressiveness by potentiating the activity of key growth, invasion, and survival pathways. Intriguingly, many of the pro-tumorigenic signaling pathways which are mechanically activated by ECM stiffness also promote glucose uptake and aerobic glycolysis, and an altered metabolism is a recognized hallmark of cancer. Indeed, emerging evidence suggests that metabolic alterations and an abnormal ECM may cooperatively drive cancer cell aggression and treatment resistance." Can anyone say Otto Warburg?
On his website 'The Fascianator,' Anthony Chrisco overviewed the first ever Harvard Medical School Joint Conference on Fascia, Cancer and Acupuncture, saying "It is in these pockets of stiffness that the cancer cells grow and proliferate. The end result is the growth of cancerous tumors in the body. Specifically in areas like our pelvis and thorax. I also learned how consistent rolling, yoga, massage and any other form of movement helps our lymphatic system shuttle our cellular waste so can be filtered out and eliminated." Last year, a large group of elite fascia researchers led by Langevin, Keely, Schleip, Findley, and others, published a similar study called Connecting (T)issues: How Research in Fascia Biology Can Impact Integrative Oncology in the journal Cancer Research. Take a gander at some of their cherry-picked conclusions.
"Recent advances in cancer biology are underscoring the importance of connective tissue in the local tumor environment. Inflammation and fibrosis are well-recognized contributors to cancer, and connective tissue stiffness is emerging as a driving factor in tumor growth. Physical-based therapies have been shown to reduce connective tissue inflammation and fibrosis and thus may have direct beneficial effects on cancer spreading and metastasis. Pathologic processes involving chronic inflammation and tissue fibrosis result in stiff connective tissue; this is likely a bidirectional feedback, as emerging evidence points to tissue stiffness itself being a contributor to the fibrotic process. In addition, there is evidence that these factors are important in cancer biology as well. Although the importance of connective tissue or stroma in cancer was first hypothesized over a century ago, cancer research has predominantly focused on the neoplastic transformation of the cancer cells themselves. However, the last decades have seen a growing interest in the factors within the “soil” that may influence cancer growth, such as angiogenesis and inflammation. Indeed there is increasing evidence that inflammation and metabolic abnormalities within the cancer microenvironment are not simply a passive reaction to cancer cells, but can also drive neoplastic transformation. Complementary and integrative treatments, such as massage, acupuncture, and yoga, are used by increasing numbers of cancer patients to manage symptoms and improve their quality of life. In addition, such treatments may have other important and currently overlooked benefits by reducing tissue stiffness and improving mobility."
Why is all of this such a big deal? Think about it this way; not only are we collectively living the high carb lifestyle (HERE ---- REMEMBER THAT SUGAR IS MASSIVELY INFLAMMATORY), which leads to serious tissue densification (a breeding ground for cancer), but medicine's standard cancer therapies (namely chemo and radiation) have devastating effects on connective tissues. I have seen time and time again in my patients that have undergone these treatments that the results leave surrounding tissues hard, tough, thick, and a great deal of the time, generally immobile. Forget for a moment that this causes pain, while realizing it contributes to the vicious cycle of inflammation and cancer. Repeat. Repeat. Repeat.
For those of you interested in this topic, you could take one of Thomas Findley's (MD / Ph.D / Professor of Physical Medicine & Rehabilitation at Rutgers University) classes on DRY NEEDLING. Or if you want to deal with PATIENTS LIKE THESE, you could take courses from Walter Fritz, a renowned PT from New York who wrote the article, Myofascial Release in the Head and Neck Cancer Patient. As long as the fascia has been dealt with first (HERE), CHIROPRACTIC ADJUSTMENTS are an incredible neurological and immuno-friendly form of treatment as well. You could even try Polarity Therapy, which was developed just after WWII by Dr. Randolph Stone, an Austrian / American DO, Chiro, and Naturopath. Plus, many people are attacking the ACID (H+) / AKLALI (OH-) conundrum by consuming special kinds of water or alkali foods.
What do I personally recommend to keep your fascia supple, hydrated, and mobile, whether you are fighting cancer, trying to stay cancer-free, or simply looking to stay healthy and pain free? For starters, drink plenty of water (not fluids; water). Secondly, there are a wide variety of self-helps available for working on your own fascia (HERE for instance). Thirdly, pumping your lymphatics may require you to climb on the kid's TRAMPOLINE or maybe use a WHOLE BODY VIBRATION MACHINE. RESISTANCE TRAINING has also shown itself valuable.
And although this list is in no ways complete, there's no substitute for knocking out inflammation at its source (HERE) --- which will require you to eat some sort of ANTI-INFLAMMATORY DIET. There is also lots of information out there on treatments like CUPPING being used to pump the lymphatics. And would be easy to argue that nothing is more important that stretching (HERE, HERE, HERE, HERE, and HERE). In fact, listen to what a group of ten Harvard researchers, including Dr. Langevin, concluded in a study published in the July 2016 issue of the Journal of Cell Physiology (Stretching Impacts Inflammation Resolution in Connective Tissue).
"It is now well established that acute inflammation is accompanied by an active program of resolution that begins in the first few hours after the onset of inflammation and involves the synthesis of specialized pro-resolving mediators derived from dietary n-3 polyunsaturated fatty acids [FISH OIL]. We developed a method by which rats and mice spontaneously stretch their whole body when they are partially lifted by the tail and allowed to grasp the edge of a surface with their front paws. When held in this position, the animals spontaneously extend both front and hind-limbs, which increases the distance between shoulders and hips by 25%. This increase in shoulder-to-hip distance stretches the thoracolumbar fascia, which connects the shoulders and pelvis, and creates a shear plane deformation between its most superficial layer (aponeurosis of latissimus dorsi) and the subcutaneous tissues of the back. The results of this study show that stretching decreases inflammation, and the similar effects of active and passive stretching suggest a mechanical effect on the tissues. Connective tissue, or stroma, is increasingly recognized as an important player in both the transition from acute to chronic inflammation, as well as the resolution of acute inflammation, either through direct contact with immune cells or by inducing changes in cytokine profiles in the tissue. The influence of mechanical forces within connective tissue is potentially far-reaching since connective tissue plays multiple roles in the body: as part of the musculoskeletal system, connective tissue forms continuous, compliant layers that can both stretch and bear loads; as part of the immune system, connective tissue is both the “container” for immune exchanges throughout the body, as well as the “conduit” through which water, proteins and immune cells return to the blood via lymphatics. Given these multiple roles, it is plausible that body movements could influence immune-related processes through a cross-talk between resident stromal cells and circulating immune cells."
God forbid you ever come down with CANCER, but if you simply PLAY THE ODDS, some of you reading this either will, or maybe already have. What I want to do now is give you a bonus section on what sort of diet might (emphasis on might) actually help accentuate your healing process, while providing a "boost" to any standard therapies you may or may not choose to do. In an age when most doctors don't give a rip about what you eat while you're fighting cancer (HERE), and an equal number who wouldn't have any idea what to suggest anyway (HERE), doesn't it make sense to educate yourself?
DISCLAIMER: The information presented on this site (including this post), while directly cherry-picked from the most current peer-review available, is just that --- cherry-picked information. It is not intended to diagnose, treat, or cure diseases of any kind, including cancer. If you feel you have a disease that needs diagnosing or treating, or if you are interested in an out-of-the-box approach, please discuss this post with your physician. Please realize that there is a high probability of receiving a deer-in-the-headlights look.
WHAT KIND OF DIET IS BEST?
DR. DAVID GORSKI is an intriguing guy. He's not only one of the nation's most renowned breast cancer surgeons, he's a research scientist with a Ph.D in cellular physiology. Along with a number of pals, he also happens to run the anti-quackery website mentioned in the quote above. Gorski is rabidly and unapologetically against all forms of alternative medicine. All. Period, end of story. But, like any number of his site's brethren, he has to pretend that everything the medical community does is based on "SCIENCE". In other words, he seems to believe that the science-based medicine (which also happens to be the name of his site) that I call "EVIDENCE-BASED MEDICINE" here on my site, is the be-all, end-all, proving beyond a shadow of a doubt that the only effective treatments of sickness and disease (IN THIS CASE CANCER) are drugs, chemo (many types, including immunotherapy), radiation, and surgery. Enter Dr. Thomas Seyfried.
Compared to crackpots like me, Seyfried and those like him have proven much tougher targets of Gorski's vitrol. You see, Dr. S is part of the club. He's part of academia. And he thinks like Warburg. In fact, check out the 2012 book he wrote called Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer, and listen to one of the many glowing Amazon reviews; this one by Dr. Stephen Strum.
"I am a board-certified medical oncologist with 30 years experience in caring for cancer patients and another 20 years of research in cancer medicine dating back to 1963. Seyfried's is the most significant book I have read in my 50 years in this field. It should be required reading of all cancer specialists, physicians in general, scientific researchers in the field of cancer and for medical students. I cannot overstate what a valuable contribution Thomas Seyfried has made in writing this masterpiece."
What exactly is it that has made Dr. Seyfried so popular with so many people, yet so vilified by others? He's a huge proponent of using the Ketogenic Diet to help those with cancer. The premise that DR. WARBURG proved scientifically --- that cancer needs sugar to survive. Take away cancer's sugar supply and you at least start pulling the rug out from under it. And what's really cool is that this is the work that Seyfried does in his lab at Boston College on a day-to-day-to-day basis.
How does one go about starving cancer of sugar? The KETOGENIC DIET of course (preferably done PALEO STYLE, using only organic fats). I recommend the Ketogenic Diet to enough people (it's been mainstream medicine's treatment of choice for SEIZURE DISORDERS for decades) that you can find it on my ONLINE PATIENT HANDOUTS. Allow me to leave you with videos on the Cancer / Lymphatics connection by Drs. Schleip, Findlay, and Langevin, as well as Doctor Seyfried's Cancer as a Metabolic Disease with Metabolic Solutions lecture.
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IS THERE A SMARTER WAY TO PRACTICE MEDICINE?
- NO IMAGING FOR NON-COMPLICATED LOW BACK PAIN: What can I tell you about imaging the low back? In most cases, what you see on the X-ray or MRI has little correlation to the patient's symptoms (HERE and HERE). What's interesting is that we are seeing this in KNEE PROBLEMS, SHOULDER PROBLEMS, and numerous other areas as well. It helps explain why MRI'S are overrated, and why increasing numbers of doctors are telling their patients with certain problems not to bother with the MRI until they are actually ready to have surgery.
- DO NOT RUN LABS, IMAGE, OR PRESCRIBE ANTIBIOTICS FOR RUN-OF-THE-MILL UPPER RESPIRATORY INFECTIONS: Science tells us that something like 90% of all upper respiratory infections (colds, FLU, sore throats, tonsillitis, laryngitis, SINUS ISSUES, EAR INFECTIONS, etc) are viral (they don't respond to antibiotics). Furthermore, science has also shown that a healthy immune system will take care of the huge majority of the other 10% of upper respiratory infections (the bacterial infections) on it's own. ANTIBIOTICS are a slippery slope because with 80% of your immune system being made up of the bacteria that live in your Gut (HERE), these drugs destroy your immune system as they take care of (OR "TRY" TO TAKE CARE OF) infections. Study after study shows that the major difference between people with URI's who take antibiotics and those who don't take antibiotics is that the antibiotic group tends to get recurrent infections. And if you destroy your GUT HEALTH with antibiotics, your chances of developing a wide array of seemingly unrelated health problems (INCLUDING CANCER) skyrocket (HERE).
- NO PSA TESTS, EXCEPTING VERY SPECIFIC CIRCUMSTANCES: It's been known for a very long time that the PSA TEST (Prostate Specific Antigen) is not a great test because of the crazy numbers of false positives / false negatives.
- NO LONG-TERM PROTON PUMP INHIBITORS: Because of the absurd number of side effects, Proton Pump Inhibitors (otherwise known as PPI'S) are one of the worst drugs you can take. Besides causing large numbers of issues by creating a problem called hypochlorhydria; since strong acid is protective against a wide range of microorganisms, it's not surprising that PPI-weakened stomach acid is highly linked to several kinds of dysbiosis (HERE), which are in turn frequently linked to EPITHELIAL MEMBRANE HYPER-PERMEABILITY, which is itself a hallmark of most chronic illness. BTW, if you take a PPI, look at the label and notice that it warns against using the drug for more than two weeks at a time, more than three times per year.
- OTHERS THAT DIDN'T MAKE THE LIST: The Swiss only tried to implement their top 5 because they believed that doing more would be too difficult. One that was on the cusp of being top-five was "No Bone Density Tests (DEXA) for Women Under 65". To see why for over two decades I have been warning my female patients that bone density tests are one of the biggest scams going, follow THESE LINKS. Honestly, rather than mention others by name, most can be found HERE.
I bring all this up because yesterday a study was published in the European Journal of General Practice (How Do Swiss General Practitioners Agree with and Report Adhering to a Top-Five List of Unnecessary Tests and Treatments?) meant to show how good a job Swiss physicians were doing at following said recommendations. Although the authors concluded that, "awareness and acceptance of 'Smarter Medicine' appear to be high among Swiss GPs," they also concluded that only, "62% knew of 'Smarter Medicine." Just realize that the results of our national programs are definitely less than 62%
That's right; even though most of you were probably not aware, the United States has actually had two similar programs (Choosing Wisely and Less is More) whose purpose is to use the "BEST EVIDENCE" to cut out the tests and procedures (there are many) that are most responsible for something known as OVERDIAGNOSIS & OVERTREATMENT. Be aware that with our per-capita consumption of healthcare at over $10,000, the stratospheric trajectory, with no end in sight, shows that American healthcare as we currently know it is becoming more UNSUSTAINABLE with every passing day.
What I am not advocating here is the KIND OF HEALTHCARE SYSTEM that Lancet was touting a few weeks ago. What I am suggesting is that it is more critical than ever to start taking care of your family's health. It's time to realize that your doctor can't do it for you --- your health is up to you. Take a look at THIS VERY COOL POST to see various ways that people just like you (overweight, degenerative diseases, autoimmune diseases, pain, etc) are turning their lives around 360 degrees. Every day I see people who got sick and tired of being sick and tired and decided to do something about it. You can to!
WHAT EXACTLY ARE FASCIAL ADHESIONS AND WHY IT IS SO IMPORTANT TO DO WHATEVER IS NEEDED TO BREAK THEM?Read Now
WHY BREAKING FASCIAL ADHESIONS MIGHT JUST BE
THE MOST IMPORTANT THING YOU DO TODAY
Inflammation presents a conundrum to friction-free fascia. On one hand it's critical for normal healing processes and should be harnessed. But on the other, if there is too much inflammation, rest assured there will be problems --- lots of problems (HERE). Furthermore, it's critical to realize that the end result of too much inflammation, no matter where said inflammation is (local or systemic), is always the same --- fibrosis. FIBROSIS is just what it sounds like; fibrotic tissue that is otherwise known as SCAR TISSUE (microscopically it tends to look and act more like a HAIRBALL than well-combed hair). Fibrosis leaves people in a quandary --- a FULL-BLOWN CONUNDRUM that I have written about repeatedly. Considering that fibrosis is America's leading cause of death, I sincerely hope folks are getting the message. Enter Dr. Lawrence Wilson.
Dr. Wilson is an MD (BS from MIT) who was a protege of the brilliant biochemist, Dr. Paul Eck. The focus of their clinical practice was mineral balancing, as well as pioneering the use of hair analysis to diagnose these imbalances. I was turned on to their work two decades ago when I attended a number of Dr. Janet Lang's "Integrated Endocrinology" seminars. Read these cherry-picked statements from Dr. Wilson's article titled Adhesions.
"In the body, an adhesion is an abnormal attachment or stickiness between two or more body tissues. Adhesions are a type of scarring or scar tissue that causes two tissues to stick together in an abnormal way. Adhesions may also be viewed as a kind of substitute physical and chemical structure that can develop in the body. In other words, adhesions can replace or substitute for other structures such as muscles, tendons, ligments and even bones that have become weakened or are out of place, or are not functioning for some other reason. In this case, the adhesions are compensations and adaptations to some kind of weakness or other problem in the body. Adhesions are always a toxic adaptation or condition. Adhesions can interfere with the blood supply and the nerve supply to various parts of the body. They also restrict bodily movement and cause poor posture. For these reasons, adhesions often cause disease and shorten a person’s lifespan. In some cases, they become vicious cycles, in which case they are even worse. The most common site of adhesions is in the fascia layers, which are under the skin. However, they can occur at other sites, including the cell membranes, the intercellular substance and matrix, the muscles, tendons, ligaments, skin, organs and elsewhere. In all cases, they involve a hardening, toughening or fibrosis of the body tissues. The main cause of adhesions appear to be inflammation that is not correctly resolved. Unresolved inflammation is often, or perhaps always due to nutritional imbalances, but may also be caused by a trauma such as a surgery, a fall, or something else. Inflammation may also be due to an infection. What is called scarring is nothing more than adhesions in the tissues that are visible, or can be felt or palpated with one’s hand. Unfortunately, most adhesions cannot be felt. They go undetected and are not dealt with by most medical and holistic doctors and practitioners."
After discussing the "conundrum" I mentioned earlier (he refers to it as a vicious cycle), Wilson goes on to talk about many of the same things I deal with on my site, including the fact that both CHIROPRACTIC ADJUSTMENTS and THERAPY are a waste of time if these adhesions --- the scar tissue that occurs mostly in the FASCIA LAYER --- are not properly dealt with first. Dr. Wilson has his own nutritional protocol for dealing with inflammation that while certainly not the same, shares many of the same traits as PALEO. And while nutrition is also an integral part of my OVERALL PROTOCOL for helping patients regain their lives as well as SOLVING THEIR OWN BACK OR NECK PAIN, there is another principle I agree with him on as well. "Medical drugs often subtly irritate, damage and congeal the tissues. These are among the “adverse effects” of these drugs. In fact, allopathic remedies cause so much adhesion damage that I predict that someday most of them will be outlawed." Tough to argue that we don't take WAY TOO MANY DRUGS!
I an article called Fascia and Inflammation, Kevin M. Cronin, a PT and owner of several Chicago area Physical Therapy clinics, said this of the connection. "Nearly all painful conditions are accompanied by inflammation of the fascia. Fascia is the connective tissue that is abundant throughout the entire body and covers all nerves, arteries, veins, and internal organs of the body. Fascia is filled with millions of nerve endings and also contains smooth muscle cells, so it can contract if injured or traumatized, and also cause skeletal muscle to tighten. The inflammatory chemicals make those same nerve endings even more sensitive, so that now it takes only takes a very mild strain to cause more inflammation, muscle spasm, and pain." So, fascia is everywhere; and when it is attacked by inflammation, it tends to not only create scar tissue, but to become HYPER-SENSITIZED (see link for Dr. Chan Gunn's amazing work). Although not as hard-line as Wilson, Cronin's article also warned of the dangers posed by trying to deal with inflammation via drugs (HERE or HERE).
Because fascia is so important to your body's ability to move and maintain NORMAL POSTURE (something spoken of by both Cronin, Wilson, and the guy we are going to talk about next), it obviously has important biomechanical properties attached to it (no pun intended). Closely related to both engineering and physics, biomechanics is simply the application of mechanical principles to biological systems (tissues, cells, organs, limbs, joints, etc, etc). Three weeks ago, McGill University engineer, Dr. Mark Driscoll, published a paper called Fascia - The Unsung Hero of Spine Biomechanics, in which he discussed the various roles that fascia plays as a tissue whose unique properties allow it to be used to gain mechanical advantage in a variety of situations (FASCIA & BIOMECHANICS).
"Over the last decade fascia has gained acknowledgement as a player in biomechanics by way of conveying mechanical forces directly or indirectly. The spine is a biomechanical marvel in regards to its intricate control and performance. However, because of such complexities many things can go wrong, perhaps why the spine is responsible for plaguing so many with pain. The role of fascia in spinal stability has yet to be fully understood but several novel and valuable discoveries have been made. Clinically, many researchers have shown and alluded to the role of the thoracolumbar fascia (TLF) in spine stability. The TLF is believed to play a role in transferring forces during coordinated activities and, consequently, such important function may be coupled with pathologies and clinical observations of TLF dysfunction. Mechanically, the tension in the TLF is regulated by many muscular attachments spanning the spino-pelvic region and by the intra-abdominal and muscular pressures. From a rehabilitation or treatment approach, the aforementioned biomechanical role of fascia offers an option upon which to plan and treat musculoskeletal disorders. Once a dysfunction sets it, regardless of its etiology, compensatory patterns may worsen by way of the novel biomechanical notion of physiological stress shielding."
I am a firm believer that ignoring the adhesions that routinely accumulate in the THORACOLUMBAR FASCIA of those struggling with CHRONIC BACK PAIN OR SPINAL DYSFUNCTION is a huge but commonly made error. We could easily take this concept a step further by saying the same thing about chronic neck pain as it relates to the CERVICAL FASCIA. In other words, as I mentioned earlier, it's not that I am against STRETCHING, therapy, chiropractic adjustments, RESISTANCE EXERCISES, or any number of other treatments so frequently used to address musculoskeletal issues (I suppose at times INVERSION might put on this list), but these have to be done after the facial adhesions are dealt with, which is especially true in severe cases. In fact, it's why I have said for a very long time that in many cases, BREAKING SAID ADHESIONS must be intense (yes, there may actually need to be BRUISING involved).
For many reasons, lots of people are squeamish about bruising. The funny thing is that it's not usually the patient, but the practitioner (or maybe the spouse or co-worker). My experience is that people who have hardcore chronic pain (EVEN THOSE WHOSE PAIN MAY HAVE CENTRALIZED), couldn't give a rip if you bruise them or not --- if you can show them quick results (I'll show you just how quickly in a moment). For instance, I had a female patient yesterday who 8 years ago decided to have a non-malignant tumor removed from her neck, just above her collar bone. The resultant adhesions had disabled her, not allowing her to move her neck at all side-to-side. Her cervical ROM was about 90% better in 10 minutes (stupid me, I was too busy to take the time to do a before and after video). Like I said, GOOD RESULTS SPEAK FOR THEMSELVES.
I bring this up because a year ago, Elisha Celeste wrote an article called Fascia, Fat Shaming and Cellulite – Are You Saying Yes to Self Abuse, or Self Love? Although she was specifically picking on the people who use ASHLEY BLACK GURU'S FASCIA BLASTER DEVICE here, her point was that if a treatment meant to deal with Fascial Adhesions causes bruising, it's too aggressive --- a point that's not uncommon among bodyworkers.
"Is there such a thing as “good” bruising? I’ve never heard that until now. A bruise is a soft tissue injury. Small capillaries have broken open, spilling blood into the surrounding tissue. Swelling and inflammation occur because the body isolates that area to STOP the bleeding and heal the damage by sending repair hormones to that spot. There is no one on this planet that can convince me that having bruises... is a good thing and a sign of healing my fascia. I proudly and happily make the claim, as a fascia release expert, that there is absolutely NO need to bruise yourself to get healthy fascia."
I would never pick on Elisha here, because frankly, it sounds like she is doing some very cool things in her practice and helping a ton of people. However, because I personally hate seeing the same patients over and over and over for the exact same thing, I 'proudly and happily' want to make a claim as well. I tell my new patients that if I am going to be able to help them, they'll know after one treatment (THAT WOULD BE ONE AS IN ONE). Not that one treatment is usually enough to totally solve many of the messes they bring in to me, but they'll know). I honestly don't know of anyone else making similar claims (it's why a visit to see me is so BLASTED SIMPLE).
BTW, Elisha is absolutely right about much of what she said. When bruising occurs and inflammation is released (remember that it's SYSTEMIC INFLAMMATION that is so bad, and that a certain amount of LOCAL INFLAMMATION is critically necessary to ensure a proper and productive healing process --- HERE), it sets in motion a cascade of chemical, neurological, and mechanical events. The "hormones" that are released to the bruised / inflamed area (you can see these HERE or HERE) are actually the GH-like growth factors that turn the metabolic / anabolic crank in people with long-standing severe adhesions. No, I don't bruise everyone who darkens the doors of my clinic; not even the majority. If, however, you have a chronic problem that is not responding to anything else, I'll give you the option of seeing if a Tissue Remodeling treatment is something you'd like to try. We already know clearing out adhesed fascia is a big deal for pain relief, but let's talk now about why this is important for problems other than pain.
A 2015 article by a group of very famous fascia researchers (Fascia Research IV: Basic Science and Implications for Conventional and Complementary Health Care) dealt with some of this. In this paper they discussed a new technology that is in many cases allowing practitioners to actually image fascia (DIAGNOSTIC ULTRASOUND) because the layers will start "sticking" or adhering together. "The structural organization of fascia into sheet-like layers with multiple orientations, attachments and its intimacy with muscle groups provides fascia with a distinctly functional anisotropy (directional variability)." When these sheets become "adhesed" to each other, it causes a wide array of problems. What sorts of problems? Here is a small sampling of a common problem that has little -- at least initially -- to do with pain.
"AT Still, MD posited a connection between cancer and fascia more than 100 years ago. Epidemiological studies show that persons with diseases of increased systemic fibrosis such as scleroderma have a much higher rate of cancer. People, who exercise, particularly resistance or weight training, are less likely to die of their cancer (and other diseases). It has been noted that both cancer and the surrounding tissues become stiffer. Stiffening of the extracellular matrix is a hallmark of cancer. The tumor associated ECM shows increased collagen deposition and crosslinking which stiffens the tissue, and increased tumor cell and fibroblast contractility which in turn increases the tension in the tissue, leading to further remodeling and stiffening. Mechanosignalling and cellular tension foster increased tumor aggressiveness. In response to mechanical cues from the ECM, cells modulate their shape and nuclear architecture which then remodels the ECM. Tumor cells show increased anaerobic glycolytic metabolism. There is emerging evidence of a connection between the altered ECM stiffness and these metabolic changes. Nutrition plays a role in reducing inflammation. The anti-nflammatory diet is [not only helpful for treating] musculoskeletal conditions, but is also useful for cardiac conditions and for cancer."
This is not so much different than some of what DR. INGBER & LANGEVIN have proposed --- that fascia is a factor in all (or at least many) disease processes. Much of this has to do with the fact that intact and healthy fascia is a full-blown PROPROICEPTIVE POWERHOUSE. Furthermore, even though AT STILL recognized a century ago that CANCER was related to fascia, 90 years ago WARBURG DISCOVERED that cancer was fed by the "glycolytic metabolism" that these authors discussed (the body fermenting sugar).
The associated cancer made the ECM thick or 'DENSIFIED', causing even more inflammation and subsequent mechanosignalling (MECHANOTRANSDUCTION --- turning mechanical signals into electrical impulses). The authors went on to say that this mess can be effectively treated (not always cured, but treated) by adding PROPER NUTRITION to whatever else you happen to be doing as treatment (remember that virtually all disease processes have similar starting points -- HERE). A huge problem, however, is that the medical community pays little more than lip service for using diet to treat much of anything --- especially cancer (HERE, HERE, and HERE). (MORE ON THE CANCER / FASCIA CONNECTION)
Beyond GIVING HELPFUL INFORMATION to both local and OUT OF STATE / INTERNATIONAL PATIENTS on a day-to-day basis, I created a completely free generic protocol that most of you can use to start taking your life back (HERE). This is important because regardless of how much my treatment helps you with your pain, a failure to deal with the underlying inflammation that is still on the loose will assure you that sooner or later your problem will return --- probably with several nasty friends. If you liked this post on fascia, be sure to check out my 160 others on the topic as well (HERE). Oh; and don't forget to like, share, or follow on FACEBOOK as well.
SUGAR INDUSTRY CAUGHT WITH THEIR HAND IN THE COOKIE JAR: YET ANOTHER PROOF THAT SCIENCE IS BOUGHT AND PAID FORRead Now
THE "SCIENCE" BEHIND ONE OF THE
MANY LIES YOU GREW UP BELIEVING
For a very long time I have told you that your level of GUT HEALTH is critically important to almost every function of your body, including your IMMUNE SYSTEM FUNCTION and your WEIGHT. What's interesting is that Project 259 initially revealed that rats fed a diet high in sucrose (white table sugar) actually had lower levels of blood triglycerides (fat) than rats fed a conventional diet of "cereal meals, soybean meals, whitefish meal, and dried yeast, fortified with a balanced vitamin supplement and trace element mixture." What their research did not initially reveal is that these mice were raised and kept "germ free" (sometimes lab animals are purposely grown and then kept in an environment that makes sure there are no microbes either inside of them or outside of them). What did these conflicting results and hidden information really mean?
The authors of this study that came out in yesterday's issue of PLoS Biology (Sugar Industry Sponsorship of Germ-Free Rodent Studies Linking Sucrose to Hyperlipidemia and Cancer: An Historical Analysis of Internal Documents) realized the bait and switch, concluding that these "results suggested to SRF that gut microbiota have a causal role in carbohydrate-induced hypertriglyceridemia." In other words, the high sugar diet was fouling the MICROBIOME of certain mice in the study, causing them to gain weight (obviously via inflammatory pathways).
So, like any other huge corporation with huge amounts of money at stake, Big Sugar pulled the plug and, "terminated Project 259 without publishing the results." In the immortal words of SNL's "Church Lady" character, 'Isn't that special?' This, folks, is what's known throughout the scientific medical community as INVISIBLE & ABANDONED RESEARCH, and unfortunately accounts for about half of all studies done in this field. Don't like what you're seeing? Just bail on the whole mess and figure out a better way to set up the study so as to get the results that those signing your paychecks are looking for.
Oh, I forgot to mention that SRF also determined, just like our old friend DR. OTTO WARBURG had done thirty five years earlier in the late 1920's, that these increased amounts of dietary sugar also happened to be associated with increased incidence of certain cancers. Here is a quote taken directly from the Sugar Association's study, "No credible link between ingested sugars and cancer has been established." Realizing they had stumbled onto the mother load of BS, the researchers for this PLoS Biology study, all from the University of California San Francisco (they work with DR. ROBERT LUSTIG) and all with rather impressive credentials), concluded that (ahem, if listening to corporate lies makes you sick, I strongly suggest you have a certified barf-bag or triple-bagged trashcan handy for the resultant spew)......
"The Sugar Association, a United States sucrose industry trade association (which has organizational ties to SRF, the International Sugar Research Foundation, and ISRF’s successor, the World Sugar Research Organisation), has consistently denied that sucrose has any metabolic effects related to chronic disease beyond its caloric effects. On January 5, 2016, the Sugar Association issued a press release criticizing findings from a study published in Cancer Research using multiple mouse models that suggested that dietary sugar induces increased tumor growth and metastasis when compared to a non-sugar starch diet. Our study contributes to a wider body of literature documenting industry manipulation of science. Industries seeking to influence regulation have a history of funding research resulting in industry-favorable interpretations of controversial evidence related to health effects of smoking, therapeutic effects of pharmaceutical drugs, the relationship between sugar-sweetened beverage consumption and weight gain or obesity...."
All I can say is thank God that at least a little bit of this fraudulent research is finally coming to light. If you want to learn more about the academic battle that led to these studies --- the battle between DR. ANCEL KEYS and DR. JOHN YURDKIN --- in relationship to what the medical community has been telling us we should be eating for the past fifty years, just follow the links. And for those of you looking to get off the medical merry-go-round, take ten minutes to READ THIS. Oh, if you liked today's post, you might enjoy my regular column on oxymoronically-named EVIDENCE-BASED MEDICINE.
GIVE THE PEOPLE WHAT THEY WANT
WHAT TOPICS ARE YOU LOOKING FOR?
Sincerely, Russ Schierling
ANOTHER WAY TO DESTROY FASCIAL ADHESIONS
Donnie, like my friend JARED, is an elite level strength athlete. Donnie's accomplishments in the strength world are rather impressive (INSANELY IMPRESSIVE would be more accurate --- he's the only person to total over 3,000lbs), but that's not what interests me most about him. As I sat here yesterday morning recovering from my second HERNIA SURGERY in six months --- right and left (yeah, I'll be back seeing patients on tomorrow morning), trying to figure out something I might be able to do so that these never have to be repeated, I came across some of Donnie's Devious Devices. Obviously this guy's mind is always on overdrive.
Thompson, like many other brilliant thinkers, stumbled onto something so revolutionary, yet so simple, that it made me stop and take notice. Almost a decade and a half ago, thanks to his incessant badgering, a group of Donnie's training partners realized that he was onto something big. After using KETTLE BELLS to roll people's bodies out since 2004, a few years ago Donnie started creating "devices" specifically meant to work in a similar capacity to FOAM ROLLERS --- only imagine foam rollers made not of foam, but out of heavy steel. Really heavy steel. With the X-wife weighing in at a whopping 135lbs (and an 'X-husband' that weighs??????), it's obviously not for the wimpy or faint of heart. Why do I bring all of this up in today's post?
It seems that even though there is not much research on Donnie's novel method of BREAKING FASCIAL ADHESIONS, not only have he and his lifting mates seen some fantastic results using his creations, but it's catching on elsewhere as well. Named "Body Tempering" by Thompson, there are actually a significant number of elite strength athletes using his creations, as well as several NFL and NCAA Division I football teams. What's the method behind Donnie's madness? I guess in many ways it's not so much different than something I recently ran across in an old coffee table book I own, Chiropractic, An Illustrated History. Here's a quote from someone writing about the famed British sea captain and explorer, Captain Cook, after he found his way to Tahiti in the 1700's.....
Twelve giantesses immediately fell upon him pummeling and squeezing unmercifully with their plump, lively hands, until his joints cracked and all his flesh felt like misused blubber. After fifteen minutes of this, the released victim got up. To his astonishment he felt immediate relief.
As a pencil-necked geek on the outside looking in, what's my opinion these rollers? I haven't tried it yet but honestly; PDC (pretty darn cool)! Firstly, I love Donnie Thompson's entrepreneurial spirit. I admire small businessmen in general, and sincerely wish him even more success than he's already had. Secondly, I love the way he thinks, as well as his creativity and outside-the-box way of looking for novel solutions to common problems. One of the more amazing things I saw on his site was Donnie taking his invention, the "Fat Bells" (ball-like semi-solid hollow dumbells that you actually put your hand inside of), screw two of them together (it took him less than 5 seconds), and then using the resulting mutant creature in similar fashion to an X-wife. All of which begs the question, how do these things really work?
I've talked at length on my site about DAVIS' LAW of TISSUE DEFORMATION (HERE as well). H.G. Davis was a renowned Civil War-era surgeon who rightly realized, like Dr. Wolf did with bones before him (see links on Davis for info on Wolf), that soft tissues would remodel themselves in response to mechanical stresses put upon them. The problem is, if there aren't enough of these mechanical stresses running around (or if the stresses never really change), then the tissues will inevitably shorten --- a common phenomenon that I refer to in my clinic as "TETHERING". What else do we know? If you are putting the kinds of mechanical stresses on MUSCLES and other connective tissues that Donnie and his crew are on a regular basis (LIGAMENTS, FASCIA, TENDONS, etc), said tissues are forced to adapt --- they have no choice. These adaptations are not anything novel and aren't much different than the physical adaptations that occur from lifting weights or engaging in other forms of training (it's known as getting in shape).
Comparing the effects that elite athletes try and achieve by training at altitude (peer review shows that high altitude training leads to increased EPO production, increased hematocrit, increased hemaglobin, etc, etc); in his piece called The Complete Guide to Foundations & Fallacies of Tissue Regeneration, Dr. John Rusin talked about things like BIOTRANSFORMATION and vasodilation, as a couple of the numerous ways that the body would try and adapt to Body Tempering (he likened it to RBFT or Restricted Blood Flow Training).
"Tissue tempering stimulates specific changes/adaptations due to its progressive and direct compression to the tissue. As with all forms of mechanical compression and shear, a reduction of tissue tightness involving fascia, muscle, veins, organs and nerves have been observed both scientifically and anecdotally. The specific changes seen with tissue tempering can also be extrapolated from recent well documented studies of occlusion training showing increased blood flow and circulating growth factor hormones that stimulate protein synthesis following treatment. An agreeable yet not documented finding with occlusion training such as tissue tempting is that it may in fact aid in ridding toxins specifically from the fascia, veins and nerve encasement’s by means of increasing vasodilation, NO2 production, and local hyperemia."
While some of these effects are vascular and/or endocrine, others are undoubtedly due to the mechanical nature of the training itself, which results in something called MECHANOTRANSDUCTION (turning mechanical energy into electrical impulses). Interestingly enough, mechanotransduction also happens to be (along with TENSEGRITY) the property that allows fascia to act as a second nervous system (HERE) --- a tough yet elastic PROPRIOCEPTIVE POWERHOUSE if you will. Bottom line, whether you are an elite athlete or AN ATHLETE WANNABE like me, there are some interesting principles at play here that Donnie Thompson had the vision and wherewithal not only to notice, but to harness and market as well. Oh; I almost left out the link to DONNIE'S SITE as well as a link to a list of my 150+ articles on fascia (HERE). Enjoy!
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MORE REASONS YOU CAN'T TRUST BIG PHARMA
A chief reason for a free media is for them to be able to report on government vice. In other words, we have Freedom of the Press so that media outlets can tell common citizens about instances of governmental corruption without fearing for their lives (just don't mention this to Seth Rich's family). Similarly, we have many medical media outlets whose job is to report on what's new in the scientific, medical, and pharmaceutical industries. In many cases, although not always, this pertains to reporting on new research or medical "breakthroughs". Many of you may not be aware of the recent fallout (☢) surrounding this topic.
MEDICAL MEDIA OUTLETS ARE TAKING MONEY FROM BIG PHARMA hand-over-fist and then trying to suggest that it doesn't cloud their judgment or affect the stories they print. Furthermore, practicing physicians are doing the same thing. Only since it's illegal for industry to offer doctors cash-for-prescribing, one of the more common ways to work around this pesky little problem is to do just what our politicians have done --- give short little talks ("speeches") for payments that could only be described as exorbitant (a great and hilarious example of this can be found HERE). We see the very same outcomes happening in the results of studies that have been done on the docs who create the "GUIDELINES" that everyone else in their profession is forced to follow. When studies are actually done on this those who create said guidelines, they show that these guidelines are bought and paid for.
Not quite two decades ago, the editor of the New England Journal of Medicine showed the world how big this problem is by asking a question via the title of an editorial; Is Academic Medicine for Sale? Few people would know who she is if DR. MARCIA ANGELL had not answered her own question so brutally. But it's obvious few got her memo. Just one short month ago today, Peer Journal Preprints (Industry Payments to Physician Journal Editors) had this to say about the sad state of affairs of journal editors who, like Angell, happen to be physicians. Pay attention to these cherry-picked results.
"In 35 journals 333 of 447 'top tier' editors met inclusion criteria as US-based physician-editors. Of these, 212 (63.7%) received any industry-associated payments in the study period. In an average year during the study period, 141 (42.3%) of physician-editors received any payments directed to themselves (rather than their institutions). A substantial minority of physician-editors receive direct payments from industry within any given year. More robust and specific editor financial conflict of interest declarations may be appropriate given the extent of editors’ influences on the medical literature."
So, while not everyone was on the take, there were two editors who collected more than 1 million dollars each in this study. But the fun doesn't stop there. One week later the British Medical Journal published a study called Payments by US Pharmaceutical and Medical Device Manufacturers to US Medical Journal Editors: A Retrospective Observational Study. Five researchers from the University of Toronto, concluded that the problem may be even worse.
"Our finding that editors of high impact journals (in specialties such as cardiology, gastroenterology, and endocrinology) receive larger payments than the typical practicing physician of the same specialty should raise questions. It is well recognized that pharmaceutical and medical device makers target physician 'thought leaders' for lucrative consulting and advisory roles. The rationale for such a strategy is that these leaders can influence both their physician peers and trainees to boost sales of products. Our finding suggests that, not surprisingly, editors at influential journals are attractive to industry; indeed, the same traits that make an individual attractive to an influential journal as a candidate for an editorial role would likely make that individual attractive to industry. We found that industry payments to journal editors are common and can be substantial. Moreover, many journals lack clear and transparent editorial conflicts of interest policies and disclosures. Journal editors should reconsider their conflict of interest policies and the impact that editor relations with industry may have on public trust in the research enterprise."
When it comes to medical research, it is being financially conflicted at every turn of the crank. What do I mean? For instance, these journals are full of advertisements --- in many cases for the very drugs or devices whose studies are being published. And then there's the issue of reprints. Drug manufactures frequently request large numbers of study-reprints, paying top dollar for them (most studies are not free, more on that shortly). These reprints are then used by the pharmaceutical company to promote their product by essentially saying, "hey, look how good our new medication turned out in this 'peer-reviewed' study." A couple of questions.
Why, if most of this research is being done in public facilities and universities (or in private facilities using public dollars) do you --- the American taxpayer --- have to pay for the results of these studies? Spend any real amount of time on PubMed like I do, and you quickly realize that while most study's abstracts are free, the actual studies usually are not (I would guess that this number is about 10-15%). The cost of obtaining these studies in their entirety is anywhere from $4.00 for a half day digital "rental," on up to several hundred dollars ($199.00 is a very common price for a study). Thus, when Big Pharma tells a certain journal that it needs "X" number of reprints of a certain study (think in terms of the "speeches" discussed earlier) the financial windfall for said journal could be substantial. And unfortunately, it is apparent that there are far too few editors of far too few journals who aren't so comfortable and cozy as to willingly bite the hand that is feeding them.
Lastly, I just loved the Orwellian term from one of the quotes above, "THOUGHT LEADERS". Speaking of thought leaders, are you aware of the #1 way Big Pharma's thought leaders continually manipulate the research so that it always seems to come out in their favor? Can anyone say INVISIBLE & ABANDONED STUDIES? Although I have written about this phenomenon extensively (see link), the problem of not reporting negative findings has gotten so bad that believe it or not, a major medical institution (The European College of Neuropsychopharmacology) is now offering a prize of 10,000 Euros for the best paper showing negative results. In an article called World’s First 'Negative Findings' Science Prize Aims to Tackle Publication Bias, ZME Science says of this problem...
"Unpublished negative scientific results can lead some research groups on unnecessary false tracks. Simply put, if you’d know there’s a good chance the research will come up blank before starting, you might choose not to engage and use limited resources in some other project. Unpublished data is effectively a waste of valuable real and human capital, particularly in the face of the reproducibility challenge. According to a recent study, irreproducible biomedical research costs the US economy alone $28 billion each year. Over 50% of published biomedical data cannot be reproduced, as startling as that may sound."
And there it is folks, not only is industry burying their negative results; of the results that are published, a significant percentage cannot be reproduced --- many experts believe this number to be over 50% (HERE). Even though I love looking at medical research, this post shows why it all needs to be taken with a grain of salt, which is doubly true for those still touting EVIDENCE-BASED MEDICINE as the pinnacle of truth and virtue. The problem is, I just showed you THE OTHER DAY in my piece on Metals in Vaccines that science isn't doing what it claims to be able to do simply because it can't --- it's not capable (HERE). For those of you interested in why, just follow some of the links. And for those of you interested in addressing potential underlying causes of you chronic health conditions or chronic pain, be sure and read THIS SHORT POST.
EVER WONDER WHY THE FLU VACCINE IS SO INEFFECTIVE?
WONDER NO MORE
It's all a vicious cycle, where every year, the powers that be use large amounts of tax-payer dollars on campaigns warning us to prepare for the flu apocalypse because THIS YEAR IS GOING TO BE THE WORST FLU SEASON EVER. And then, when all is said and done, you read an article by some government official (usually buried in the back of the newspaper) saying that this year's flu vaccine turned out to be something like 13.3% effective (HERE). And now we finally (and supposedly) know why --- it's the eggs that the flu virus used to make the vaccines are grown in. The Scripps scientists opened their study with a revelation that should catch everyone's attention; "The effectiveness of the annual influenza vaccine has declined in recent years." According to these authors, it all has to do with the way that a certain mutation in the virus interacts with certain mutations in the egg protein. Listen to part of the news release from the Scripps Research Institute (How Flu Shot Manufacturing Forces Influenza to Mutate: Egg-Based Production Causes Virus to Target Bird Cells, Making Vaccine Less Effective)
"X-ray crystallography to show that—when grown in eggs—the H3N2 subtype mutates a key protein to better attach to receptors in bird cells. Specifically, there was a mutation called L194P on the virus’s hemagglutinin glycoprotein (HA). This mutation disrupts the region on the protein that is commonly recognized by our immune system. This means a vaccine containing the mutated version of the protein will not be able to trigger an effective immune response. This leaves the body without protection against circulating strains of H3N2. In fact, analysis shows that the current strain of H3N2 used in vaccines already contains this specific mutation L194P on HA. “Vaccine producers need to look at this mutation...."
Any time I get around flu vaccine research, my BS detector has a tendency of going off. Want to know what tripped the switch this time? Allow me to show you that this problem is almost as old as the hills. It's nothing new, and it sounds to me like it's yet another excuse for why efficacy for the various forms of flu vaccines for various populations (HERE, and HERE for example) is functionally zero (if you think I'm being too harsh, click the links).
Over 22 years ago, the August 1995 issue of the Journal of Virology published a study very similar to the one being discussed today called Selection of a Single Amino Acid Substitution in the Hemagglutinin Molecule by Chicken Eggs Can Render Influenza A Virus (H3) Candidate Vaccine Ineffective. The study essentially concluded that thanks to mutations, (which are extremely common), growing these viruses in mutated eggs should be ended. "Thus, it is recommended that in the selection of vaccine candidates, virus populations with the egg-adapted HA Lys-156 substitution be eliminated." Yes, I realize that this is a bit different mutation than the one we were discussing earlier, but the principles are the same. Said mutations caused a vaccine that was described with words such as "nonprotective," "poorly recognized," and that, "egg-grown HA Lys-156 variant induced an AFC profile vastly different from that elicited by the other two reassortant vaccines." With this being the case, why should be be surprised that almost a quarter century later, this latest PLoS study is saying things things similar?
"Despite the first commercial influenza vaccines being approved in the US more than 70 years ago, complete and broad protection from an influenza vaccine has remained out of reach. Furthermore, in the past decade, the effectiveness of the seasonal vaccine against H3N2 viruses has been particularly low. ...the vaccine effectiveness was estimated to be only 33% for H3N2 viruses. Studies have attributed this low effectiveness of the H3N2 vaccine to the egg-based production process. Although eggs provide a cost effective way to grow influenza virus, the abundance of avian-type receptors on the chorioallantoic membrane often results in selection of variants that increase binding to avian-type receptors, and reduce binding to human-type receptors. More importantly, these egg-adaptive substitutions on the HA have also been shown to impact antigenicity, leading to a decrease in vaccine effectiveness. As annual vaccination remains the major preventive measure against influenza virus, it may be beneficial to accelerate consideration of alternative approaches for influenza vaccine production to optimize the protective effectiveness of the vaccine."
You don't have to read very far between the lines to see just how bad this really is for the H3N2 part of the vaccine, all of which begs the question of just how common the H3N2 flu virus is concerning overall flu statistics? Listen to what Sino Biological said in their article titled Influenza Hemagglutinin (HA) subtypes and Flu Virus Strains. "The influenza virus is divided into three main types, Influenza A, Influenza B, and Influenza C, which are distinguished by differences in two major virus surface proteins. Influenza A virus is the most common flu virus infecting humans, animals, and birds. There are 16 different types of hemagglutinin A (HA) and 9 different types of NA, therefore, there are potentially 144 different subtypes of influenza A viruses. Among them, two subtypes of influenza A, H1N1 and H3N2, most commonly infect humans." In their entry, Wikipedia took this concept a step farther by saying that the, "H3N2 is increasingly abundant in seasonal influenza."
What do I come away from this with? One of my friends, a brilliant MD who not only practices, but teaches at a major university and leads an online study group of about 70 physicians, researchers, functional medicine specialists, nutritionists, experts in athletic performance, etc (I will not mention his name here), recently stated on the message board that there will never be a universal flu vaccine. This post explains why. With so many potential combinations of virus, as well as both the viruses and the growing medium (in this case eggs) showing constant genetic variations and mutations, one's immune system is rarely encountering the same virus in real life exposure that it encountered via immunization. And even when it does, efficacy is downright poor. For more information on the crappy nature of Flu Vaccines, including my piece called TWENTY REASONS YOU DON'T WANT A FLU SHOT, simply click the link.
WHIPLASH, NECK PAIN,
& POST-SURGICAL ARTHRITIS
A POTENTIAL BREAKTHROUGH FOR HANNAH
I was diagnosed with loss of cervical curve years ago. I have had multiple car accidents (not my fault - went through a windshield head first as a 4 year old in 1974, whiplash from a rear end accident at age 9, then again at age 18). I have DDD in lumbar spine - failed back surgery x2. I also have idiopathic peripheral polyneuropathy (maybe from Lyme) in my hands, arms, legs and feet. I tend to fall a lot. I tripped the other day and landed head first into a dresser. This of course did nothing for my chronic neck pain!
Anyway I had to change pain management people and my current one is claiming that nothing is ever done for a reverse neck curve and that I am exaggerating the pain from my C5, C6, C7 osteophytes and diagnosed cervical DDD. I have had cervical facet rhizotomy in the past and can no longer look up to the top shelf in the grocery store, nor tip my head all the way back to get the last drop when taking a drink. I have limited side to side movement (being blind in right eye from car accident - I often have to turn my entire upper body around to the right to see out of my left eye). I can't watch TV or sit for too long without using a pillow to prop my head up.
Years ago I used to use a cervical foam collar on occasion for support. I can no longer get it under my chin. I also used to use an inflatable pump collar for traction (over the door traction made me nauseous and dog ate pump). Current provider won't do anything for me (order new collars, etc). She states "it is what it is". I currently get pain medication from her - which is being restricted all over the country so I'm limited in my choices of providers/doctors. (Although her office hung up on me the other day so maybe I should go elsewhere.)
Can you just tell me if indeed I should be concerned with the pain, symptoms and limitations with my neck? I'm 47 and I don't want to spend the rest of my life looking down. Thank you so much for your time.
Firstly, yes you should be concerned about the limitations in your neck because any time there is chronic pain, there is a chance of you ending up with CENTRAL SENSITIZATION. And with the kind of chronic restriction you are describing, there's a 100% probability of ending up with DEGENERATIVE ARTHRITIS (DJD / DDD). Secondly, females are much more prone to most disease processes, and particularly most AUTOIMMUNE DISEASE PROCESSES, when compared to their male counterparts (BLEEDING EVERY MONTH can be problematic as well). Add to this the fact that HEAD INJURIES ARE HEAVILY-LINKED TO AUTOIMMUNITY (a fact seen by the three severe MVA's in her youth), and you can see why this needs to at least be discussed --- especially in relationship to IPP.
IPP (Idiopathic Peripheiral Polyneuropathy) is a NEUROPATHY at multiple sites of the body, with an "officially" unknown cause. The NIH's Periphrial Neuropathy Fact Sheet (What is Peripheral Neuropathy?) shows why various forms of PN can be so devastating, "An estimated 20 million people in the United States have some form of peripheral neuropathy, a condition that develops as a result of damage to the peripheral nervous system. Damage to nerves that supply internal organs may impair digestion, sweating, sexual function, and urination. In the most extreme cases, breathing may become difficult, or organ failure may occur. Peripheral nerves send sensory information back to the brain and spinal cord, such as a message that the feet are cold. Peripheral nerves also carry signals from the brain and spinal cord to the muscles to generate movement. Damage to the peripheral nervous system interferes with these vital connections. Peripheral neuropathies may also be caused by a combination of both axonal damage and demyelination."
Although there were many reasons for said neuropathy listed in this article, the most common was said to be trauma ("such as from automobile accidents..."), while the one with the biggest entry was autoimmune ("Autoimmune diseases can lead to nerve damage. When the tissue surrounding nerves becomes inflamed, the inflammation can spread directly into nerve fibers. Over time, these chronic autoimmune conditions can destroy joints, organs, and connective tissues, making nerve fibers more vulnerable to compression injuries and entrapment."). Relief of neuropathy symptoms can often be accomplished with LOW LEVEL LASER THERAPY. However, long-term regeneration of almost any neuropathy and/or autoimmune condition is going to require a change of diet (be aware that many neurological issues --- including some kinds of neuropathy --- respond quite well to a KETOGENIC APPROACH.
Not sure from her history whether Hannah actually has Lyme Disease or not, but Lyme is certainly a wildcard. Even though there are many claims out there, I am not aware of anyone consistently getting great results with Lyme patients. If she has had Lyme, the standard therapy is to give many months (3-15) of ANTIBIOTICS, hoping that the antibiotics kill the bacteria before it BEFORE THEY MESS YOU UP TOO BADLY (remember that 4/5ths of your body's immune system resides in the Gut in the form of bacteria --- HERE). If I see a patent who has autoimmunity (whether the disease has been named or not --- in many cases they are not because no one knows for sure what the auto-antigen is or how to test for it) or been on hardcore antibiotics, it is time to start thinking about the most potent treatment that few people are familiar with --- FMT. Now for the arthritis.
What we are seeing over and over again in the practice of medicine (I just saw a study on this topic on KNEES yesterday) is that it is almost impossible to look at the results of an imaging test, whether for DISC HERNIATION, DEGENERATIVE ARTHRITIS, or ROTATOR CUFF PROBLEMS, and in most cases, have any real idea whether or not the problem you see on the film is causing the patient's symptoms. This is because said symptoms correlate very poorly (emphasis on poorly) with imaging studies --- yet another of the MANY DIRTY LITTLE SECRETS that Big Medicine doesn't want you to know about. Would I be surprised that Hannah's pain doctor told her that FHP (FORWARD HEAD POSTURE) doesn't mean anything? Certainly not --- no more than I am surprised by dentists who claim that a mouthful of CAVITIES is kind of like death and taxes; just another one of life's unfortunate inevitabilities.
So, beyond addressing these issues systemically (this is done by addressing INFLAMMATION), you'll need to address the neck issue itself. This could be a challenge for you Hannah because if you can no longer get a soft collar under your chin, it tells me that you have a whale of a case of FHP. How do I suggest you deal with this? You cannot start with adjustments. Neither can you start with stretching or strengthening exercises. You will have to go through both PHASE I and PHASE II of the simple rehab protocol I suggest for people with these sorts of issues.
The good news for you Hannah is that this does not have to be one of those scenarios that always seems to end like this --- "the normal cost is fifteen grand, but if you sign up today, we'll give it to you for half that". By the way, it is my experience that medications from the BIG FIVE FAMILY, or procedures like Radio Frequency Ablations (RFA's are otherwise known as Facet Rhizotomies), rarely work for the long-term because they do absolutely nothing to address underlying causes (unfortunately the ablated nerves always grow back, many times with a vengeance).
The cool thing for many of you in the same situation as Hannah is that I have put together a general protocol that will help at least some of you (HERE is the link to our Case Studies). Don't get me wrong, as much as I with it would, I did not say it would help all of you, but best guess is that it's better than a 50/50 --- and it's not going to make you worse. Furthermore Hannah, you are going to have to step out of the box. Making healthcare decisions based largely on what your insurance provider will pay will get you in trouble in way too many cases (the DAKOTA TRACTION UNITS, for instance, are dirt cheap).
To see my GENERAL PROTOCOL for relieving inflammation in those of you struggling with chronic pain, chronic inflammatory degenerative diseases, autoimmunity, or even some conditions that you have probably been told are "GENETIC," simply follow the link and start reading.
Dr. Schierling completed four years of Kansas State University's five-year Nutrition / Exercise Physiology Program before deciding on a career in Chiropractic. He graduated from Logan Chiropractic College in 1991, and has run a busy clinic in Mountain View, Missouri ever since. He and his wife Amy have four children (three daughters and a son).
Brain Based Therapy
Can You Help
Cardio Or Strength
Cold Laser Therapy
Death By Medicine
Degenerative Joint Disease
D's Of Chronic Pain
Evidence Based Medicine
Gluten Cross Reactivity
Ice Or Heat
Jacks Fork River
Leaky Gut Syndrome
Number One Health Problem
Platelet Rich Therapy
Post Surgical Scarring
Re Invent Yourself
Rib And Chest Pain
Scar Tissue Removal
Sleeping Pills Kill
Stay Or Go
Stretching Post Treatment
Tensegrity And Fascia
The Big Four
Thoracic Outlet Syndrome
Whole Body Vibration